Bestow Major Curse (Reversible)

By touching a creature, the caster bestows a major curse upon it. The caster can choose any effect from the list of major curse effects (see list). The creature is allowed a saving throw vs. spell; success negates the curse. Neither dispel magic nor remove curse can rid a creature of this effect. Only a wish or remove major curse is an effective remedy. The spell requires some personal possession of the creature (this is not consumed in the casting).

The reverse of the spell, remove major curse, counters any of the major curse effects.